中国药科大学药学院硕导介绍:杨勇

姓名:杨勇 性别:男 出生年月:1976年12月 职称:副教授 学院:药学院 研究方向:主要从事基于转化医学的分子靶向抗肿瘤药物研究与开发。
20. Lu N, Gao Y, Ling Y, Chen Y, Yang Y, Gu HY, Qi Q, Liu W, Wang XT, You QD, Guo QL. Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. Life Sciences. 2008 23;82(17-18):956-63.
21. Chen J, Gu HY, Lu N, Yang Y, Liu W, Qi Q, Rong JJ, Wang XT, You QD, Guo QL. Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cells. Life Sciences. 2008;83(3-4):103-9.
22. Gu H, You Q, Liu W, Yang Y, Zhao L, Qi Q, Zhao J, Wang J, Lu N, Ling H, Guo Q, Wang X. Gambogic acid induced tumor cell apoptosis by T lymphocyte activation in H(22) transplanted mice. Int Immunopharmacol. 2008, 8(11):1493-502.
23. Zhao J, Qi Q, Yang Y, Gu HY, Lu N, Liu W, Wang W, Qiang L, Zhang LB, You QD, Guo QL. Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with Gambogic acid. Eur J Pharmacol. 2008, 589(1-3):127-31.
24. Lu N, Ling Y, Gao Y, Chen Y, Mu R, Qi Q, Liu W, Zhang H, Gu H, Wang S, Yang Y, Guo Q.. Endostar suppresses invasion through down-regulating the expression of matrix metalloproteinase-2/9 in MDA-MB-435 human breast cancer cells Experimental Biology and Medicine.2008, revised. (Corresponding author)
25. Jun Y, Guo QL, You QD, Zhao L, Gu HY, Yang Y, Zhang HW, Tan Z, Wang X. Gambogic acid induced G2/M phase cell cycle arrest via disturbing CDK7 mediated phosphorylation of CDC2/P34 in human gastric carcinoma BGC-823 cells. Carcinogenesis. 2007,28(3)632-8.
26. Qinglong Guo, Li Zhao, Yong Yang,Hongyan Gu, Guoliang Song, Na Lu, Jian Xin , Qidong You. Anti-hepatitis B virus activity of wogonin in vitro and in vivo. Antiviral Research .2007, 74(1)16-24.
27. Yang Hu, Yong Yang, Qi-Dong You, Wei Liu, Hong-Yan Gu, Li Zhao ,Kun Zhang, Wei Wang, Xiao-Tang Wang, Qing-Long Guo. Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity. Biochemical and Biophysical Research Communications 351 (2006) 521–527. (Co-first author)
28. Wang W, Guo QL, You QD, Zhang K, Yang Y, Yu J, Liu W, Zhao L, Gu HY, Hu Y, Tan Z, Wang XT. The Anticancer Activities of Wogonin in Murine Sarcoma S180 both in Vitro and in Vivo. Biol Pharm Bull. 2006;29(6):1132-7.
29. Wang W, Guo Q, You Q, Zhang K, Yang Y, Yu J, Liu W, Zhao L, Gu H, Hu Y, Tan Z, Wang X. Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721.Anticancer Drugs. 2006 17(7):797-805.
30. Yong Yang, Xing Liu, Yan Long, Fang Wang, Jian-Hua Ding, Su-Yi Liu, Ye-Hong Sun, Hong-Hong Yao, Hai Wang, Jie Wu, Gang Hu. Activation of mitochondrial ATP-sensitive potassium channels [!-
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improves rotenone-related motor and neurochemical alterations in rats. The International Journal of Neuropsycopharmacology, 2006;9 (1):51-61.
31. Hua CHEN, Yong YANG, Hong-hong YAO, Xing-chun TANG, Jian-hua DING, Hai WANG, Gang HU. Protective effects of iptakalim, a novel ATP-sensitive potassium channel opener, on global cerebral ischemia-evoked insult in gerbil. Acta Pharmacol Sin 2006, 27(6):665-72. (Co-first author)
32. Liu X, Wu JY, Zhou F, Sun XL, Yao HH, Yang Y, Ding JH, Hu G. The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells. Neuroscience Letters, 2006; 394(2):131-5.
33. Yong Yang, Xing Liu, Yan Long, Fang Wang, Jian-Hua Ding, Su-Yi Liu, Ye-Hong Sun, Hong-Hong Yao, Hai Wang, Jie Wu, Gang Hu. Systemic administration of iptakalim, a novel ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats. Journal of Neuroscience Research, 2005; 80 (3): 442-449.
34. Yang Y, Liu X, Ding JH, Long Y, Wang F, Yao HH, Hu G. Effects of iptakalim on rotenone-induced cytotoxicity and dopamine release from PC12 cells. Neuroscience Letters, 2004; 366 (1), 53-57.
35. Sen Wang, Li-fang Hu, Yong Yang, Jian-hua Ding, Gang Hu. Studies of ATP-sensitive potassium channels on 6-hydroxydopamine and haloperidol rat models of Parkinson’s disease: Implications for treating Parkinson’s disease? Neuropharmacology, 2005; 48 (7): 984-992.
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